Our Partners

At the heart of Open Targets is a consortium of complementary partner institutions that bring their respective expertise to collaborative projects that improve how we systematically identify and prioritise drug targets.


News

Immunotherapy success could be predicted with new biomarkers

20 January 2026

The deletion of two cancer genes, CHD1 and MAP3K7, improves how well tumours respond to cancer immunotherapy and could be used as biomarkers to help predict which patients are most likely to benefit from treatment, new research shows.

Researchers at the Wellcome Sanger Institute, Open Targets, Netherlands Cancer Institute and their collaborators used a powerful gene-editing tool called CRISPR in a novel approach that cultured tumour cells together with immune cells from the same in...

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Our Principles

A systematic approach

Systematically identify and prioritise the best targets to safely and effectively treat rare and common diseases

Open Exchange of Ideas

We are committed to making our data, methods and results publicly available as soon as possible to foster an open exchange of ideas

Multidisciplinary collaboration

We believe in non-exclusive partnerships that foster the free exchange of ideas, expertise, and data



Introducing the official Open Targets Platform Model Context Protocol

David Ochoa

12 January 2026

Open Targets Platform 25.12 has been released!

Sir Target

10 December 2025

Open Targets Platform 25.09 has been released!

Sir Target

17 September 2025

Why Mallory Freeberg is creating a perturbation catalogue

Helena Cornu

23 July 2025

Case study: an Open Targets Platform MCP server

Helena Cornu

17 July 2025

Open Targets Platform 25.06 has been released!

Sir Target

18 June 2025

An atlas of tissue-specific protein-protein associations helps to prioritise targets for drug discovery

Helena Cornu

6 May 2025

Open Targets Platform 25.03 has been released!

Sir Target

19 March 2025

A step-change in common disease genetics in the Open Targets Platform

David Ochoa

19 March 2025

Case study: gget’s new Open Target module

Helena Cornu

30 January 2025

Open Targets Platform 24.09 has been released!

Sir Target

18 September 2024

Three reflections from David Hulcoop's first year as Executive Director

David Hulcoop

13 August 2024

Tutorial: Introducing the Open Targets Standalone Deployment Tool

Manuel Bernal Llinares

2 July 2024

Open Targets Platform 24.06 has been released!

Sir Target

19 June 2024

How Ana Cvejic built an immune atlas of lung cancer

Helena Cornu

23 May 2024

Integrating pharmacogenetics data: a new lens for target prioritisation

Irene López Santiago, April Shen

9 May 2024

Open Targets Platform 24.03 has been released!

Sir Target

20 March 2024

Q&A with Lucy Sibbring, an intern with the Open Targets data team

Helena Cornu

29 February 2024

Open Targets Platform 23.12 has been released!

Sir Target

30 November 2023

Q&A with Jason Menkiti, an intern with the Open Targets data team

Helena Cornu

8 November 2023

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