Open Targets is an innovative, large-scale, multi-year, public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation.

Visit the Open Targets Platform which integrates public domain data to enable target identification and prioritisation, or the Open Targets Genetics Portal which identifies targets based on GWAS and functional genomics. We complement data integration with large scale systematic experimental approaches to support target identification, prioritisation and validation. Check out our latest papers describing our experimental target identification approaches in oncology, neurodegeneration, and immunity and inflammation.


News

Open Targets releases a COVID-19 Target Prioritisation Tool

Wednesday 29 July 2020 | Cambridge, UK

Open Targets is excited to announce the release of our COVID-19 Target Prioritisation Tool, an interactive, open source web portal that integrates a number of key public datasets and publications to facilitate systematic exploration of host and viral targets as well as potential treatments for COVID-19.

To learn more about the tool, visit our blog.


Our Partners

At the heart of Open Targets is a consortium of complementary partner institutions that bring their respective expertise to collabortive projects that improve how we systematically identify and prioritise drug targets.


Our Principles

A systematic approach

Systematically identify and prioritise the best targets to safely and effectively treat rare and common diseases

Rapid publication

We are committed to rapid publication and making data, methods and results publicly available as soon as possible

Open collaboration

We believe in non-exclusive partnerships that foster the free exchange of ideas, expertise, and data


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Accessing Open Targets Genetics using GraphQL

Jarrod Baker | August 06, 2020

A demonstration of how to use the GraphQL interface to explore the Genetics portal and prepare an...

Open Targets releases our COVID-19 Target Prioritisation Tool

Andrew Hercules | July 29, 2020

Open Targets is excited to introduce our COVID-19 Target Prioritisation Tool, an interactive web ...

Open Targets Platform 20.06 has been released!

Denise Carvalho-Silva | June 17, 2020

We have a new release of the Open Targets Platform: new disease terms including COVID-19, new che...

Open Targets Platform: adding FDA data with Scala and Spark

Jarrod Baker | June 05, 2020

Leveraging Spark and Scala to implement a performant ELT pipeline to integrate the FDA Adverse Ev...

Open Targets Platform 20.04 has been released!

Denise Carvalho-Silva | April 27, 2020

We have a new release of the Open Targets Platform with new target safety data, new target tracta...