Our Partners

At the heart of Open Targets is a consortium of complementary partner institutions that bring their respective expertise to collaborative projects that improve how we systematically identify and prioritise drug targets.

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UMAP of the data from the project

Cellular study maps gene activity changes across more than 50 gut cell types in Crohn’s disease

15 June 2026

The latest IBDverse study identifies the genes expressed in Crohn’s disease, revealing a lasting ‘molecular scar’ in the gut lining.

A detailed cellular study of Crohn’s disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterise each cell type and those whose activity shifts in disease, uncovering new molecular and cellular signatures of immune activity in the gut lining.

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Our Principles

A systematic approach

Systematically identify and prioritise the best targets to safely and effectively treat rare and common diseases

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Open Exchange of Ideas

We are committed to making our data, methods and results publicly available as soon as possible to foster an open exchange of ideas

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Multidisciplinary collaboration

We believe in non-exclusive partnerships that foster the free exchange of ideas, expertise, and data

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