A partnership to transform drug discovery through the systematic identification and prioritisation of targets

Open Targets is an innovative, large-scale, multi-year, public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation.

Visit the Open Targets Platform which provides an integration of public domain data to enable target identification and prioritisation.

Visit the Open Targets Platform

Open Targets welcomes new partner Takeda

Cambridge, 4 December 2017 – Open Targets announced today that Takeda has joined its pioneering public-private collaboration to transform drug discovery by improving the success rate for developing new medicines. Takeda is a global, research and development-driven pharmaceutical company with expertise in oncology, gastroenterology (GI) and central nervous system (CNS) disease that will complement the offerings of GSK, Biogen, the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EMBL-EBI), and build on the initiative’s success.

Full press release


Generating and interpreting the data required to identify a good drug target demands a diverse set of skills, backgrounds, evidence types and technologies, which do not exist today in any single entity. Open Targets brings together expertise from five complementary institutions to systematically identify and prioritise targets from which safe and effective medicines can be developed.

Our goals are to:

  • Systematically find the best targets to safely & effectively treat disease
  • Help others find good targets
  • Get those targets adopted into drug discovery pipelines

We currently focus on oncology, immunology and neurodegeneration through an R&D framework that can be applied to all aspects of human disease. We believe that evidence generated in the most human relevant systems showing which targets are causing disease will have a significant impact on the successful development of new medicines. To build a good therapeutic hypothesis we need to find not only which targets are involved but also how we might alter complex disease mechanisms, and how predictive laboratory and animal results are for humans. Learn more about our science.

Open Targets is committed to openly sharing our data with the scientific community through publications, the internationally recognised databases and the Open Targets Platform. Access our resources.

We welcome discussions with new partners who share our philosophies and scientific interests. Get to know our team and find our contact details.

For more information about Open Targets please see this introductory video.